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October 17, 2011

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No real threat to eyesight

This takes us back a few years to a time when stories began to surface about adverse side effects to the use of drugs used to treat erectile dysfunction. Men had begun to report changes to their eyesight. One or two men apparently lost their sight for short periods of time. On many occasions when side effects are reported under the Postmarketing Surveillance Program, the FDA does not react immediately. Sometimes, it does not react at all. Without going into the politics of its role, some critics suggest the FDA is in the pocket of the pharmaceutical industry and would never react to reports of side effects unless the evidence is too public and overwhelming to ignore. That’s what made it all the more surprising when the FDA decided to apply a watered down version of the precautionary principle to erectile dysfunction drugs. Just so we all understand, the precautionary principle says you pull a product off the market until it is proved safe. Since proving the negative is difficult, this can mean the product is off the market for a long time. With erectile dysfunction drugs, we are talking about retail sales in excess of one billion dollars in 2008. You do not mess with this market by shutting it down. The most you can do is change the label to warn users of potential dangers.

In July, 2005, the FDA issued a notice acknowledging rare reports of eye problems. The notice did not accept there was evidence of a link between the drugs and the vision problems. It simply advised men affected to seek emergency aid if the rare event affected them. From a scientific point of view, there is a strong likelihood of a link. These drugs target PDE5 in the body. The relevant arteries in the eye are controlled by PDE6. The drug may not be completely specific in all bodies and the effect on PDE5 may shade into PDE6. That said, the pharmaceutical industry had a marketing problem. Even though everyone acknowledged these were extraordinarily rare events, the release of the notice by the FDA did cause some alarm. The industry therefore commissioned some research which was published this year in the Archives of Ophthalmology. It’s good news. Some 250 men men with good eyesight and erectile dysfunction were recruited and given various dosages of the drugs, one pill per day for six months. Their vision was routinely monitored throughout the trial period. There were no significant differences found between their sight before and after the period. There was no measurable effect of any kind in any of the men (except their erections, of course).

One word of caution. To be able to generalize from one sample to the population at large, there should be more men included in the trial. Only 250 men is not statistically significant. That said, this is a detailed study and the results are encouraging. Viagra has not been given an absolutely clean bill of health, but this comes close. If the industry can be persuaded to recruit a sufficient number for the next trial, we can arrive at a definitive result. While we wait, buy viagra online with complete confidence. There is no evidence anyone has ever lost their sight because of this drug.

It won’t make you go blind

It’s strange how the warnings given when you are young can still haunt you years later. Very early, parents and teachers muttered darkly that masturbation will make you go blind. This is a terrible warning to give a growing child. Everything in the world is shiny and new. You are just starting to drink in all the sights, sounds and new experiences. To suggest you will be denied sight if you pursue just a little personal pleasure in private is unkind to say the least. It goes way beyond the use of guilt and ordinary fear. This is the demonization of a natural activity that helps you learn about the way in which you body works. At a time when you should be exploring the relationship between your body and your emotions, you are left with nothing but frustration. Until you find a willing partner that is. Then the world takes on a different look and feel as “natural” emotions start to flow. Except you then run into a whole new set of barriers where parents expect you to wait until marriage before trying sex. Abstinence is the preferred message in modern sex education for growing children.

By a curious coincidence, the labels on the drugs used to treat erectile dysfunction also refer to various risks connected to eyesight. This is not a threat made to deter adults from sexual activity. Rather, it refers to a side effect experienced by some of the men who take the drugs. A very small number of men have reported a slight blurring of their vision, often accompanied by a blue tinge to what is seen. One or two have experienced a complete loss of vision. This latter is so remote a possibility that it can almost immediately be dismissed. The average man is never going to find his vision disappearing. To discover the extent of the risk of mere blurring, there has been a recent clinical trial involving almost 250 healthy men. None of the men had any problems with their vision and their eyes were tested before, during and after taking the relevant drugs (or a placebo) over a six month period.

The results were recently published and show no change to the eyesight of any of the men who participated. There are two minor comments that take the edge of the goodness of the news. The first is that the participants were given low doses of viagra. In the real world, the men who reported problems were all taking up to the maximum daily dose. Thus, the strength of the evidence is limited by the need to produce an ethical study. Researchers should not knowingly design a clinical trial likely to injure the participants. Secondly, none of the participants had any existing problem with their eyes. Again, the men who reported problems all had less than perfect vision. The study therefore suggests that it’s perfectly safe to take viagra. It will not make you go blind if you are taking a lower dose and you have no existing problems with your eyesight. Because this represents most men, this study confirms viagra’s reputation as safe and effective.

Your eyesight is not at risk

When I was growing up, my parents and other adults took up the challenge of trying to educate me in the ways of sex. It was dangerous work, but someone had to do it. One of the first pieces of advice that stuck concerned the activity of masturbation. Although no-one would give me a demonstration of what this thing was, I was led to understand that too much of it and I would go blind. Naturally, being of a stubborn disposition, I decided to keep the activity going, hoping I was only risking one eye. This is a classic use of fear and guilt to encourage people to modify their behavior. It came alongside a similar warning that watching too much television was also bad for my eyesight. Apparently, the cathode ray tube gave off radiation that would rot the lenses and turn my retinas to jelly. Or was it that my retinas were a kind of jelly and, as with a microwave, they would be cooked and stop admitting light. The details are hazy but the message was clear. The combination of television and sex were bad for the eyesight.

Coming forward to the new century and the FDA began to receive reports through the post-marketing monitoring program that some men were experiencing problems with their eyesight when using the little blue pills. Because they were blue pills, the men claimed their vision was tinged with blue and sometimes blurry. Actually, I made that up. The men made no such claim but their vision was tinged with blue. The reason was that PDE6 changes the way the retina works and the little blue pills are designed to affect PDE5 which is in the penis. Unfortunately, the pill is not always specific, what with sex and eyes being so closely connected.

At first, this was not thought to be a serious problem but it became so when one or two men reported actual vision loss. In a billion dollar US market, the notion that men may go blind is dangerous to future sales, so an immediate new clinical trial was ordered. Well, men can relax again (except after taking the pill, of course). This October has seen the publication of the report from a six month trial. In a double-blind, randomized trial, two-thirds of the participants took the real drug and one-third took a placebo. At the end of six months, there was no measurable difference in the eyesight of the participants in both groups. Allowing for natural ageing, their eyesight was unchanged from start to finish.

It’s a little ironic after all these years to see real panic at the notion that too much sex using viagra will make you go blind. My parents would have appreciated the temporary support to their own threats relating to masturbation. Although I do admit to having to wear spectacles these days, I am no different from the millions of older men. We Boomers wear our fading eyesight with pride. Despite all the sex over the years, we have managed to make it this far with only minor short-sightedness. With a little help from viagra when our muscles tire, we can expect to enjoy many more years of sex (or, at least, we can all risk one eye with that aim in mind).

LCD vs. CRT Monitor Comparison

Text and images (scans of census records) are crisper and sharper and the LCD monitor is easier on your eyes. Monitor’s size: Traditional monitors are similar to a TV because both of them have the CRT (Cathode Ray Tube). That is the reason for its bigger size. It therefore occupies more space at the desk. It is also heavy.

However, LCD monitors have thin flat screen. Therefore occupies very less space and is lighter than the CRT monitor. LCD monitors can be fixed even on wall. Display Size: Even though the display size of a CRT monitor is calculated diagonally, the actual display size is smaller. For instance a 17″ CRT monitor will actually have a display size of only 16″ However, the display size of 17″ LCD monitor will have 17″ display size. Resolution: CRT monitors can show different resolutions. The resolution can be changed as required. LCD Monitors will have Native Resolution and therefore has a fixed resolution. The best resolution will be the native resolution for that LCD monitor. Viewing Direction: A CRT screen can be viewed from all directions. And from different distance. But LCD monitors cannot be viewed from all directions. LCD monitors can only be viewed straight. Therefore its viewing direction is limited. If viewed from other directions the colors will change and sometimes the vision will be unclear if not viewed straight. But in recent years the new LCD monitors have improved on this defect. Radiation Emission: The radiation emission in CRT monitors are higher. This will not be visible normally but it will affect eyesight and may cause head ache. Long term use of these monitors may even affect the eyes adversely. LCD monitors do not have this type of Radiation emission. Therefore LCD monitors are good for the eyes. Price: CRT monitors are priced very cheap. However they consume more power. LCD monitors are priced higher, but they consume less electricity. Though the electricity consumption is not very significant for personal use, it is very cost efficient in big organizations with many computers.

EyesightTag Archives

Stylish Lace Wigs

No real threat to eyesight

It won’t make you go blind

Your eyesight is not at risk

LCD vs. CRT Monitor Comparison

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